24) THE FOLLOWING ARE EFFECTS OF CORTISOL

[Editor]

a) protein anabolism
b) osteoporosis
c) potassium retention
d) depression of anterior pituitary function
e) salt and water retention

[Editor]

FTFTT

Cortisol acts via affecting gene transcription. The metabolic effects are anti-insulin leading to hyperglycaemia, and it also causes increased protein catabolism. It also causes osteoporosis via diminished collagen synthesis by osteoblasts. Excess Cortisol enhances the negative feedback mechanism resulting in a reduction in the release of ACTH. Glucocorticods have about 5% intrinsic mineral corticoid effects and hence with excess can result in salt and water retention, hypokalaemia and hypertension.

[gklau]

d) should be false. True that cortisol inhibits ACTH release, but other hormones are released as normal

[kmax]

Yeah but doesnt stipulate which ones. So theoretically it does reduce ant pit function if not for all hormones