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Anaesthesia Site Editor
Prime Minister Rank
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Join Date: Mar 2005
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57) .IN SKELETAL MUSCLE -
03-30-2005, 03:44 AM
a) actin and tropomyosin are found in the thin filaments
b) the thick filaments are myosin
c) calcium is bound by tropomyosin C
d) blood flow is dcreased by sympathetic stimulation
e) the sarcoplasmic reticulum contains calcium
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Anaesthesia Site Editor
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Re:57) .IN SKELETAL MUSCLE -
03-30-2005, 03:44 AM
ttttt
Actin ,tropomyosin and troponin with its 3 subunits C,I and T are found in the thin actin filaments. The thick filaments are made up of myosin.Blood flow is decreased by sympathetic stimulation as a result of vasoconstrictor activity,as in orthostasis and hypovolemia because the resistance of the muscle circulation increases.As in splanchnic and renal circulations this is an important regulatory mechanism of arterial pressure.
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Revise Medicine Member
Specialist Registrar Yr 3 Rank
Posts: 56
Join Date: Aug 2005
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Re:57) .IN SKELETAL MUSCLE -
08-22-2005, 01:38 AM
Calcium ia bound by troponin.
Symp stimulation causes vasodilation in skeletal muscle (fight or flight response)
(A-Z)
So I think c. and d. are false.
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Revise Medicine Member
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03-27-2006, 05:19 PM
Ca2+ binds to troponin C on the actin filaments. This interacts with troponin I and tropomysin and this complex moves awayu to expose binding sites on actin (Brandis). Therefore, (d) is T
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Revise Medicine Member
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03-27-2006, 05:20 PM
Sorry, last post should read therefore (c) is True
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