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Physiology mcq 7 Questions 91-105 Physiology multiple choice questions for the primary FRCA examination. Discuss answers and explanations area

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63) .GLUCAGON - 03-30-2005, 03:49 AM

a) stimulates insulin release
b) is secreted in increasing concentrations during starvation
c) stimulates gluconeogenesis
d) stimulates glycogenolysis
e) is secreted by the islets of langerhans


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Re:63) .GLUCAGON - 03-30-2005, 03:49 AM

TTTTT

Glucagon is a polypeptide consisting of 29 amino acids. It is synthesized and released by the A cells of the Islets of Langerhans in the pancreas (B cells synthesize insulin, D cells secrete somatostatin). The actions of glucagon (via cAMP) mainly antagonize those of insulin.
-promotes hepatic glycogenolysis, gluconeogenesis,
-promotes lipolysis
-increases insulin, growth hormone, somatostatin secretion
-increases ketogenesis
-also direct positive inotropic effect on heart
Secretion is increased by beta-adrenergic stimulation, stress, exercise, amino acids, gastrin, and starvation.


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12-01-2006, 11:13 AM

can you help me to understand how glucagon increases insulin release if it antagonises insulin action
 
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