ReviseMedicine.com Medical Training - 9) RAISED TOTAL BODY CALCIUM IS ASSOCIATED WITH

Editor · #1

a) renal calculi
b) increases in pH ( false)
c) increases in plasma phosphate
d) increases in active vitamine D
e) increased parathyroid levels

Editor · #2

ttftt
Ca is excreted by kidney, increase excretion (as in hypercalcaemia) will increase the risk of stones. Alkalosis will increase plasma protein ionisation increase Ca binding to protein, leading to tetany. Many stimuli that increase Phsphate absorption also increase Ca absorption. Active vitamin D (1, 25 {OH}2 D3 will increase Ca resorption and absorption, as do the raised PTH.

Eloise · #3

PTH increases calcium and reduces phosphate but vit D increases calcium AND phosphate, so it\'s difficult to answer c.

Tonic · #4

The picture will very much depend on the cause.The two main causes are primary hyperparathyroidism and malignancy. If it's primary hyperparathyroidism you get a high PTH despite high calcium so you will have a raised active vit D3. The phospate would be low (a hallmark of the condition) and these patients do often have a mild hyperchloraemic acidosis. If it was secondary to malignany the PTH would be low as would the active vit D3.